Abdelaal AM, Sohal IS, Iyer SG, Sudarsahn K, Orellana EA, et al. (2024). Molecular Therapy Nucleic Acids, (35)-2. PMID: TBD
Publications
Publications
Structural basis of regulated m7G tRNA modification by METTL1-WDR4
Authors: Li J, Wang L, Hahn Q, Nowak RP, Viennet T, Orellana EA, et al.(2023). Nature. Jan;613(7943):391-397. doi: 10.1038/s41586-022-05566-4. Epub 2023 Jan 4. PMID: 36599985.
METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation.
Orellana, E.A., et al. (2021). Mol Cell 81, 3323-3338.e3314. PMID: 34352207
METTL4 is an snRNA m6Am methyltransferase that regulates RNA splicing
Chen, H., Gu, L., Orellana, E.A., et al. (2020). Cell Res 30, 544-547. PMID: 31913360
Identification and validation of microRNAs that synergize with miR-34a – a basis for combinatorial microRNA therapeutics
Orellana, E.A., et al. (2019). Cell Cycle 18, 1798-1811. PMID: 31258013
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
Hinze, L., Pfirrmann, M., Karim, S., Degar, J., McGuckin, C., Vinjamur, D., Sacher, J., Stevenson, K.E., Neuberg, D.S., Orellana, E., et al. (2019). Cancer Cell 35, 664-676.e667. PMID: 30991026